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Zanubrutinib

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Zanubrutinib is a medication used to treat certain types of blood cancers, like mantle cell lymphoma and chronic lymphocytic leukemia (CLL). It belongs to a group of drugs called Bruton's tyrosine kinase (BTK) inhibitors. These drugs work by blocking a protein called BTK, which is involved in the growth and spread of cancer cells.

 

Blood cancers happen when certain types of white blood cells grow out of control. Zanubrutinib helps stop this by targeting BTK, which is like a signal that tells cancer cells to grow. By blocking BTK, zanubrutinib slows down or stops the growth of cancer cells, helping to shrink tumors and control the disease.

 

Zanubrutinib comes in the form of capsules, which are taken by mouth. It's usually taken once or twice a day, with or without food, as directed by a doctor. The dose may vary depending on factors like the type of cancer and how well the patient tolerates the medicine.

 

Like all medications, zanubrutinib can cause side effects. Some common side effects include diarrhea, nausea, fatigue (feeling tired), headaches, and muscle or joint pain. These side effects are usually mild to moderate and may improve over time as the body gets used to the medicine. However, if they become severe or bothersome, it's essential to talk to a doctor.

 

In addition to these common side effects, zanubrutinib can also cause more serious side effects that require medical attention. These may include bleeding problems, infections, heart rhythm problems, and high blood pressure. It's important for patients to report any unusual symptoms to their doctor right away.

 

Before starting treatment with zanubrutinib, it's important to tell the doctor about any other medications or supplements the patient is taking. Some medicines can interact with zanubrutinib and cause problems, so the doctor can check if it's safe to take them together.

 

Zanubrutinib is not recommended for use during pregnancy, as it can harm the unborn baby. Women of childbearing age should use effective birth control during treatment and for some time afterward. It's essential to talk to a doctor about the risks and benefits of zanubrutinib if planning to become pregnant or breastfeeding.

 

Overall, zanubrutinib is an important treatment option for certain types of blood cancers. By targeting BTK, it helps slow down or stop the growth of cancer cells, giving patients a better chance at controlling the disease and improving their quality of life. If diagnosed with mantle cell lymphoma or CLL, it's important to discuss treatment options with a doctor to see if zanubrutinib may be right for them.

 

Have any queries, book a consultation with our Oncology Clinical Specialist

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How does this medicine work

Zanubrutinib is like a superhero that fights blood cancer. It works by targeting a protein called Bruton's tyrosine kinase (BTK). Now, this protein is like a signal that tells cancer cells to grow and spread.

So, when someone has blood cancer, these signals go haywire, causing the cancer cells to multiply too quickly. Here's where zanubrutinib comes in. It blocks these signals from reaching the cancer cells, essentially putting the brakes on their growth.

By stopping the BTK protein from doing its job, zanubrutinib helps slow down or even stop the cancer cells from spreading further. It's like cutting off the fuel supply to a fire, stopping it from spreading and getting worse.

In simple terms, zanubrutinib is a medicine that helps keep blood cancer cells in check by blocking the signals that make them grow out of control. It's an important tool in the fight against blood cancer, offering hope for patients to control the disease and improve their quality of life.

Have any queries, book a consultation with our Oncology Clinical Specialist

What is useful for?

Zanubrutinib is a medicine that helps treat certain types of blood cancer. It is mainly used for:

1. **Mantle Cell Lymphoma (MCL)**: This is a rare type of non-Hodgkin's lymphoma, which is a cancer of the lymphatic system. Zanubrutinib helps control the growth of cancer cells in this condition.

2. **Chronic Lymphocytic Leukemia (CLL)**: This is a common type of leukemia in adults, affecting white blood cells called lymphocytes. Zanubrutinib slows down or stops the growth of these cancerous cells.

By targeting and blocking the signals that tell cancer cells to grow, zanubrutinib helps manage these diseases, improving the patient's chances of controlling the cancer and enhancing their quality of life.

Visit our Research Division Doctors in Online Consults for more details.

What if you miss the dose?

If you miss a dose of zanubrutinib, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose. Don't take two doses at the same time to make up for the missed one. Just continue with your regular schedule. If you're not sure what to do, ask your doctor or pharmacist for advice. It's important to take zanubrutinib regularly as prescribed to get the best results in treating your cancer.

Please book a consultation with our Oncology Clinical Specialist to know more about what happens if you miss the dose.

Will there be Side Effects

There can be side effects when using zanubrutinib. Some common side effects include:

1. **Diarrhea**: You might have loose or watery stools.
2. **Nausea**: You could feel like you want to throw up.
3. **Fatigue**: You might feel very tired.
4. **Headaches**: You may get headaches more often.
5. **Muscle or Joint Pain**: Your muscles or joints could hurt.

These side effects are usually mild to moderate and might get better as your body gets used to the medicine. However, zanubrutinib can also cause more serious side effects that need medical attention:

1. **Bleeding Problems**: You might bleed more easily, like having frequent nosebleeds or bruising easily.
2. **Infections**: You could be more likely to get infections.
3. **Heart Rhythm Problems**: Your heartbeat might become irregular.
4. **High Blood Pressure**: Your blood pressure could increase.

If you experience any unusual or severe symptoms, tell our doctor right away. They can help manage the side effects or adjust your treatment if needed.

any queries, book a consultation with our Oncology Clinical Specialist

Tell us if you are taking other medicines like:-

If you're taking other medicines along with zanubrutinib, it's important to tell our doctor. Some medicines can interact with zanubrutinib and cause problems. This includes:

1. **Prescription Medications**: Other drugs prescribed by our doctor.
2. **Over-the-Counter Medications**: Medicines you can buy without a prescription, like pain relievers or cold medicines.
3. **Vitamins and Supplements**: Any vitamins, minerals, or herbal supplements you take.

Our doctor needs to know about all these to make sure it's safe to take them with zanubrutinib. They might need to adjust your doses or monitor you more closely to avoid any issues. Keeping our doctor informed helps ensure your treatment is safe and effective.

book a consultation with our Oncology Clinical Specialist

Safety Advice : Pregnancy, Liver or Kidney Damaged

### Pregnancy:
- **Avoid Pregnancy**: Do not take Zanubrutinib if you are pregnant because it can harm the baby.
- **Use Birth Control**: If you are of childbearing age, use effective birth control during treatment and for some time after finishing it. Talk to our doctor about the best options.
- **Inform Our Doctor**: If you are pregnant or planning to become pregnant, let our doctor know before starting Zanubrutinib.

### Liver or Kidney Damage:
- **Tell Our Doctor*
*: If you have liver or kidney problems, inform our doctor. These conditions can affect how your body processes the medication.
- **Dose Adjustments**: Our doctor may need to adjust your dose or monitor you more closely to ensure the medicine is safe and effective for you.
- **Regular Monitoring**: You may need regular blood tests to check your liver and kidney function during treatment.

By following these guidelines, you can help ensure the safe and effective use of Zanubrutinib. Always keep our healthcare provider informed about any health issues or concerns.

Have any queries, book a consultation with our Oncology Clinical Specialist

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