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Trastuzumab deruxtecan

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Trastuzumab deruxtecan, also known as Enhertu, is a type of medicine used to treat certain types of cancer, especially breast cancer. It's made up of three main parts: trastuzumab, a chemotherapy drug, and a linker that joins them together.

Now, let's break it down:

1. **Trastuzumab**: Trastuzumab is a type of medication that targets specific proteins called HER2 receptors. These receptors are found on the surface of some cancer cells, especially in breast cancer. By targeting these receptors, trastuzumab works to stop the cancer cells from growing and spreading.

2. **Chemotherapy Drug**: The chemotherapy drug in Trastuzumab deruxtecan is a powerful medicine that kills cancer cells. It's like a soldier going into battle against the cancer cells, destroying them and preventing them from causing further harm.

3. **Linker**: The linker is like a bridge that connects trastuzumab and the chemotherapy drug together. This connection is important because it helps to deliver the chemotherapy drug directly to the cancer cells, increasing its effectiveness and reducing side effects on healthy cells.

 

So, how does Trastuzumab deruxtecan work?

When someone with cancer receives Trastuzumab deruxtecan through an injection into their vein, trastuzumab goes looking for those HER2 receptors on the cancer cells. Once it finds them, it attaches itself to the cancer cells. Then, the chemotherapy drug, which is now attached to trastuzumab, gets released into the cancer cells. This is like delivering a powerful punch directly to the cancer cells.

 

Once inside the cancer cells, the chemotherapy drug goes to work, damaging their DNA and stopping them from multiplying. As a result, the cancer cells are unable to grow and spread further. Eventually, they die off, helping to shrink the tumor and slow down the progression of the cancer.

Trastuzumab deruxtecan has shown promising results in clinical trials, especially for people with HER2-positive breast cancer who have tried other treatments that haven't worked well. It has been approved by regulatory agencies in various countries, including the United States and Japan, as a treatment option for certain types of breast cancer.

 

However, like all medications, Trastuzumab deruxtecan can cause side effects. Some common side effects may include nausea, fatigue, hair loss, and low blood cell counts. It's essential for patients to discuss potential side effects with their healthcare team and report any unusual symptoms they may experience during treatment.

 

In conclusion, Trastuzumab deruxtecan is a targeted therapy that combines the power of trastuzumab and chemotherapy to treat HER2-positive breast cancer. It works by specifically targeting cancer cells, delivering chemotherapy directly to them, and slowing down the progression of the disease. While it has shown effectiveness in clinical trials, patients should be aware of potential side effects and communicate closely with their healthcare providers throughout their treatment journey.

 

Have any queries, book a consultation with our Oncology Clinical Specialist

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How does this medicine work

Trastuzumab deruxtecan works like a smart missile against cancer cells, especially in breast cancer. Imagine the cancer cells have a special marker called HER2. Trastuzumab, one part of the medicine, acts like a key that fits perfectly into this marker, locking onto the cancer cells.

Once it's locked in, the other part of the medicine, a strong chemotherapy drug, gets released directly into the cancer cells. It's like sending a powerful soldier right into the enemy's camp. This drug then goes to work, damaging the cancer cells' DNA, which stops them from multiplying and spreading.

As a result, the cancer cells weaken and die off. This helps to shrink the tumor and slow down the cancer's growth. It's a targeted attack that aims to hit the cancer cells hard while causing fewer side effects to healthy cells.

Trastuzumab deruxtecan is a clever medicine that zeroes in on cancer cells, delivers a potent treatment directly to them, and helps stop the cancer from getting worse.

Have any queries, book a consultation with our Oncology Clinical Specialist

What is useful for?

Trastuzumab deruxtecan is helpful for treating a specific type of breast cancer called HER2-positive breast cancer. This means it targets cancer cells that have a certain marker called HER2. It's typically used when other treatments haven't worked well. So, if someone has HER2-positive breast cancer that's hard to treat, this medicine might be an option to help slow down the cancer's growth and improve the person's chances.

Visit our Research Division Doctors in Online Consults for more details.

What if you miss the dose?

Missing a dose of Trastuzumab deruxtecan can be serious because it's an important part of the treatment for breast cancer. If you miss a dose, it's essential to talk to our doctor right away. They can help you figure out the best course of action. Sometimes, they might reschedule the dose or adjust your treatment plan to make sure you're still getting the right care. But it's crucial not to skip doses without talking to our doctor first because it could affect how well the treatment works against the cancer.

Please book a consultation with our Oncology Clinical Specialist to know more about what happens if you miss the dose.

Will there be Side Effects

There can be side effects after using Trastuzumab deruxtecan. Some people might experience things like feeling tired, feeling sick to their stomach, losing their hair, or having low levels of certain blood cells. These side effects can vary from person to person, and not everyone will have them. It's essential to talk to your doctor about any side effects you experience. They can give you advice on how to manage them and might even adjust your treatment to help lessen the side effects. Overall, while there can be side effects, many people find that the benefits of Trastuzumab deruxtecan in treating breast cancer outweigh the potential drawbacks.

any queries, book a consultation with our Oncology Clinical Specialist

Tell us if you are taking other medicines like:-

If you're taking other medicines along with Trastuzumab deruxtecan, it's important to let our doctor know. They need to make sure that the different medicines won't interact with each other in a harmful way. Our doctor will review your medications and adjust your treatment plan if needed to keep you safe and make sure you get the best possible care. So always keep our doctor informed about any other medicines you're taking, whether they're prescription drugs, over-the-counter medications, or even supplements.

book a consultation with our Oncology Clinical Specialist

Safety Advice : Pregnancy, Liver or Kidney Damaged

If you're pregnant, have liver or kidney problems, it's important to talk to your doctor before using Trastuzumab deruxtecan. This medicine could potentially harm an unborn baby, so it's crucial to discuss any pregnancy plans with our doctor before starting treatment. Additionally, if you have liver or kidney damage, your doctor needs to know because they may need to adjust your treatment plan to keep you safe. Always follow our doctor's advice and let them know about any health conditions you have before starting Trastuzumab deruxtecan.

Have any queries, book a consultation with our Oncology Clinical Specialist

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