Larotrectinib is like a superhero medicine that fights a specific type of cancer. Here's how it works in simpler terms:Imagine your body is like a big city, and cancer cells are like troublemakers causing chaos. Now, some of these troublemaker cells have a special problem called an NTRK gene fusion. It's like they have a secret code that makes them grow too fast and spread.Larotrectinib is like a superhero with a special power: it can find these troublemaker cells with the NTRK gene fusion and stop them in their tracks. It's like putting up a big stop sign in front of the troublemaker cells, telling them to calm down and behave.When you take Larotrectinib, it travels through your body and seeks out these troublemaker cells. Once it finds them, it blocks their special code, so they can't keep growing and causing trouble. It's like cutting off their power supply.The amazing thing about Larotrectinib is that it's really smart. It only goes after the troublemaker cells with the NTRK gene fusion, leaving the good cells alone. So, it's like a superhero with laser focus, targeting only the bad guys without harming the good guys.By stopping the troublemaker cells from growing and spreading, Larotrectinib helps to shrink tumors and improve the outlook for people with this type of cancer. It's like restoring peace and order to the city, one troublemaker cell at a time.In simple terms, Larotrectinib is a superhero medicine that finds and stops cancer cells with a special problem, giving hope for a brighter future for people fighting this type of cancer.
Have any queries, book a consultation with our Oncology Clinical Specialist

Larotrectinib is helpful for treating a specific type of cancer called solid tumors with a special genetic problem called an NTRK gene fusion. It's like a special tool that targets and stops these cancer cells from growing and spreading. By doing this, Larotrectinib helps improve the chances of recovery for people with this type of cancer.

Visit our Research Division Doctors in Online Consults for more details.

If you forget to take your Larotrectinib pill at the usual time, don't worry too much. Just take it as soon as you remember, unless it's almost time for your next dose. If that's the case, it's best to skip the missed dose and take the next one as scheduled. Never take two doses at the same time to make up for the one you missed. Just stick to your regular dosing schedule. If you're not sure what to do, it's always okay to ask your doctor or nurse for advice.

Please book a consultation with our Oncology Clinical Specialist to know more about what happens if you miss the dose.

Larotrectinib, like any medication, can cause some side effects. Here are some simplified explanations of potential side effects:

1. **Fatigue:** You might feel more tired than usual while taking Larotrectinib. It's like your body needs more rest.

2. **Nausea and Vomiting:** Some people may feel sick to their stomach or vomit after taking Larotrectinib. It's like having a stomachache or feeling queasy.

3. **Dizziness:** You may feel dizzy or lightheaded while taking Larotrectinib. It's like feeling unsteady on your feet.

4. **Changes in Liver Function:** Larotrectinib can affect how your liver works, which might show up in blood tests. It's like your liver needs a little extra attention.

5. **Constipation or Diarrhea:** Some people may experience changes in bowel habits while taking Larotrectinib, such as constipation or diarrhea. It's like having trouble with your stomach or bathroom habits.

6. **Muscle Pain:** You might feel achy or have muscle pain while taking Larotrectinib. It's like having sore muscles after exercising.

7. **Skin Rash:** A rash or skin irritation may occur while taking Larotrectinib. It's like having a red, itchy patch on your skin.

It's important to remember that not everyone will experience these side effects, and some people may have different ones. If you notice any side effects or have concerns while taking Larotrectinib, be sure to talk to your doctor. They can provide guidance and support to help manage any side effects you may experience.

Have any queries, book a consultation with our Oncology Clinical Specialist

When you're taking Larotrectinib, it's important to be careful with certain medications that might not mix well with it.   

1. **Avoid Strong CYP3A4 Inhibitors:** These are medicines that can make Larotrectinib stay in your body longer, possibly causing more side effects. Examples include some antifungal drugs and certain antibiotics.

2. **Be Cautious with Strong CYP3A4 Inducers:** These medicines can make Larotrectinib less effective by reducing its levels in your body. Examples include some tuberculosis drugs and certain seizure medications.

3. **Watch Out for St. John's Wort:** This herbal supplement can interfere with Larotrectinib's effectiveness, so it's best to avoid it while taking Larotrectinib.

4. **Discuss Other Medicines with Your Doctor:** Some other medications might interact with Larotrectinib, so it's essential to talk to our doctor about everything you're taking, including prescription drugs, over-the-counter medicines, and supplements.

By being aware of these precautions and talking to our doctor, you can help make sure that Larotrectinib works safely and effectively for you.

Have any queries, book a consultation with our Oncology Clinical Specialist

When using Larotrectinib, here are some simplified safety tips to keep in mind:

1. **Follow Doctor's Instructions:** Take Larotrectinib exactly as your doctor tells you. Don't change the dose or stop taking it without talking to our doctor first.

2. **Take with Food:** Larotrectinib is usually taken with food. This can help reduce the chance of stomach upset.

3. **Keep Track of Side Effects:** Pay attention to how you feel while taking Larotrectinib. If you notice any new or unusual symptoms, let our doctor know right away.

4. **Avoid Grapefruit:** Grapefruit and grapefruit juice can interact with Larotrectinib, so it's best to avoid them while taking this medication.

5. **Stay Hydrated:** Drinking plenty of fluids can help prevent dehydration, especially if you experience diarrhea while taking Larotrectinib.

6. **Sun Protection:** Larotrectinib may increase sensitivity to sunlight, so be sure to use sunscreen and wear protective clothing when outdoors.

7. **Keep Your Appointments:** Attend all scheduled appointments with our doctor. They can monitor your progress and adjust your treatment plan as needed.

8. **Medication Check:** Inform your doctor about all medications you are taking, including prescription drugs, over-the-counter medicines, and supplements. Some medications may interact with Larotrectinib.

9. **Pregnancy and Breastfeeding:** If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of taking Larotrectinib with our doctor.

10. **Storage:** Store Larotrectinib tablets at room temperature, away from moisture and heat.

By following these safety tips and communicating openly with your healthcare provider, you can help ensure that your treatment with Larotrectinib is safe and effective.

Have any queries, book a consultation with our Oncology Clinical Specialist