Cisplatin is a clear liquid that is injected into a vein. It works as follows:- 

Cisplatin, a compound similar to bifunctional alkylating agents, attaches itself to DNA, disrupting its normal function. Once inside cells, it replaces its chloride ligands with water molecules, forming positively charged platinum complexes. These complexes then bind covalently to sites on DNA, creating cross-links within and between DNA strands, which interferes with DNA, RNA, and protein synthesis. This process occurs regardless of the cell cycle phase. Additionally, cisplatin exhibits immunosuppressive, radiosensitizing, and antimicrobial properties.

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Primary uses are to treat Adrenalcortical cancer, Anal cancer, Bladder cancer, Brain cancer, Breast cancer, Cervical cancer, Esophageal cancer, Gallbladder cancer, Gastric cancer, Germ cell tumour, Gestational trophoblastic neoplasia, Head and neck cancer, Liver cancer, Lung cancer, non-small cell, Lung cancer, small cell, Lymphoma, Hodgkin'sLymphoma, non-Hodgkin's, Mesothelioma, Neuroendocrine tumours, Nasopharyngeal cancer, Osteosarcoma, Ovarian cancer, Salivary gland cancer, Testicular cancer, Thymoma, Urothelial cancer.

Secondarily this drug is also used to treat Endometrial cancer, Lymphoma, CNS, Melanoma, Multiple myeloma, Pancreatic cancer, Penile cancer, Prostate cancer.

Research studies are going on this drug to check if this medicine can be used to treat other type of cancer. 

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Cisplatin is given by an injection please book a consultation with our Oncology Clinical Specialist to know more about what to do if you miss the dose.

Hearing problems, Bone marrow issues, Anemia, Low immunity, Nausea,Vomiting, Salt imbalance in body, Kidney issues from toxins.

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Other drugs such as some antibiotics given by vein (e.g., Tobramycin, Vancomycin), and Furosemide, Phenytoin and Pyridoxine may interact with Cisplatin. Tell your doctor if you are taking these or any other drugs as you may need extra blood tests or your dose may need to be changed.

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Cisplatin may cause sterility in men and menopause in women. If you plan to have children, discuss this with your doctor before being treated with cisplatin. • Cisplatin may damage sperm and may harm the baby if used during pregnancy. It is best to use birth control while being treated with cisplatin. Tell your doctor right away if you or your partner becomes pregnant. Do not breast feed during treatment.

Have any queries, book a consultation with our Oncology Clinical Specialist