Carmustine is a clear liquid that is injected into a vein and it is also available in the form of wafer which is placed in the brain during surgery. It works as follows:- 

Carmustine is a potent compound that easily dissolves in fats. It works as a dual-action alkylating agent, affecting both DNA and RNA by attaching alkyl groups to them. This process can lead to DNA cross-linking and the inhibition of certain enzymes through carbamoylation. Carmustine doesn't specifically target cells in a particular phase of the cell cycle. Unlike some similar agents, it typically doesn't share resistance with other alkylating agents, although there have been instances of cross-resistance between carmustine and lomustine.

Have any queries, book a consultation with our Oncology Clinical Specialist

Primary uses are to treat Brain tumours, Glioma (implantable carmustine-impregnated wafer), Lymphoma, Hodgkin’s disease, Lymphoma, non-Hodgkin’s, Multiple myeloma, Melanoma, Gastrointestinal cancer.

Secondarily this drug is also used to treat Glioblastoma (implantable carmustine-impregnated wafer), Lymphoma, cutaneous T-cell (topical carmustine).

Research studies are going on this drug to check if this medicine can be used to treat other type of cancer. 

Visit our Research Division Doctors in Online Consults for more details.

Carmustine is given by an injection, please book a consultation with our Oncology Clinical Specialist. to know about what you should do if you miss the dose.

Anemia, Decreased blood cell production, Nausea, Vomiting, Lung damage or harm, Pneumonia, Brain infection (Might cause while using carmustine wafer).

Have any queries, book a consultation with our Oncology Clinical Specialist

Other drugs like Cimetidine, Digoxin tablets, Melphalan, Phenytoin may interact with carfilzomib. Tell your doctor if you are taking these or any other drugs as you may need extra blood tests or your dose may need to be changed.

Have any queries, book a consultation with our Oncology Clinical Specialist

Carmustine may cause sterility in men and menopause in women. If you plan to have children, discuss this with your doctor before being treated with carmustine. • Carmustine may damage sperm and may harm the baby if used during pregnancy. It is best to use birth control while being treated with carmustine. Tell your doctor right away if you or your partner becomes pregnant. Do not breast feed during treatment.

Have any queries, book a consultation with our Oncology Clinical Specialist