Carfilzomib is a clear liquid that is injected into a vein.It works as follows:- 

Carfilzomib is a medication that blocks a key enzyme called the proteasome, responsible for breaking down cellular proteins. By inhibiting this enzyme, carfilzomib triggers the accumulation of proteins tagged for destruction, leading to cell cycle arrest and ultimately, cell death. Unlike some other inhibitors, carfilzomib's effects are long-lasting because it irreversibly binds to the proteasome. This drug also shows promise in causing fewer side effects like peripheral neuropathy compared to similar medications. It mainly works by halting the cell cycle at the G2-M phase.

Have any queries, book a consultation with our Oncology Clinical Specialist

Primary uses are to treat Multiple myeloma.

Secondarily this drug is also used to treat Waldenström’s macroglobulinemia

Research studies are going on this drug to check if this medicine can be used to treat other type of cancer. 

Visit our Research Division Doctors in Online Consults for more details.

Carfilzomib is given by an injection, please book a consultation with our Oncology Clinical Specialist. to know about what you should do if you miss the dose.

Anemia, Low immunity, Low platelet count, Cardiac failure, Diarrhea, Nausea, Fatigue, Fever, Swelling in the legs, ankles, or feet, Infusion reaction, Liver enzyme increase, High calcium level in blood.

Have any queries, book a consultation with our Oncology Clinical Specialist

Other drugs may interact with carfilzomib. Tell your doctor if you are taking these or any other drugs as you may need extra blood tests or your dose may need to be changed.

Have any queries, book a consultation with our Oncology Clinical Specialist

Carfilzomib may damage sperm and may harm the baby if used during pregnancy. It is best to use birth control while being treated with carfilzomib and for a time after treatment ends. For female patients, continue birth control for one month after treatment. For male patients, continue birth control for three months after treatment. Tell your doctor right away if you or your partner becomes pregnant. Do not breastfeed during treatment.

Have any queries, book a consultation with our Oncology Clinical Specialist