Apalutamide is a tablet that is taken orally and it works as follows:- 

Apalutamide is a medication that blocks the effects of male hormones (androgens) in the body. It works by interfering with the signals that androgen receptors send to cells. This stops the receptors from moving into the cell nucleus, binding to DNA, and triggering the production of proteins that promote cancer growth. In studies, apalutamide has been shown to reduce the growth of tumors and even cause cancer cells to die. It's particularly effective because it competes strongly with androgens for binding to androgen receptors. Unlike some other drugs, apalutamide doesn't activate androgen receptors, even in cells that have a lot of these receptors.

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Primary uses are to treat Prostate Cancer

Research studies are going on this drug to check if this medicine can be used to treat other type of cancer. 

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If you miss a dose of apalutamide, take it as soon as you can if it is within 12 hours of the missed dose. If it is more than 12 hours since your missed dose, skip the missed dose and go back to your usual dosing times.

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Nausea, Vomiting, Skin rashes, Underactive thyroid, Abdominal pain, Fatigue, Falls, Fractures, High cholesterol levels, Low pottasium levels, high blood sugar, High triglyceride levels, Rash, Hypertension

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Other drugs such as Gemfibrozil, Ketoconazole, Warfarin , and Omeprazole  may interact with apalutamide. Tell your doctor if you are taking these or any other drugs as you may need extra blood tests or your dose may need to be changed. Check with your doctor or pharmacist before you start or stop taking any other drugs.

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Apalutamide may damage sperm and may harm the baby if used during pregnancy. It is best to use birth control while being treated with apalutamide and for three months after the last dose of apalutamide. It is best for male patients to use a condom during sexual activity with a pregnant woman, and a condom plus one other effective birth control method during sexual activity with a woman who may become pregnant. Tell your doctor right away if your partner becomes pregnant

Have any queries, book a consultation with our Oncology Clinical Specialist