Amivantamab is a tablet and you take it orally. It works as follows:- 

Amivantamab is a type of antibody that works to fight cancer. It attaches to two different proteins on the surface of cancer cells called epidermal growth factor receptor (EGFR) and mesenchymal-epithelial transition (MET). By binding to these proteins, amivantamab blocks their ability to receive signals, which slows down the growth of cancer cells. In models with specific mutations, amivantamab also helps break down EGFR and MET proteins, further weakening the cancer cells. Importantly, by targeting EGFR and MET, amivantamab helps activate the body's immune cells like natural killer cells and macrophages to attack and destroy the cancer cells.

Have any queries, book a consultation with our Oncology Clinical Specialist

Primary uses are to treat Lung cancer, non-small cell

Research studies are going on this drug to check if this medicine can be used to treat other type of cancer. 

Visit our Research Division Doctors in Online Consults for more details.

Weekly Cycle 1 (initial dose): If a dose is missed within 3 days of the scheduled date, the dose should be administered as soon as possible and the dosing schedule should be adjusted accordingly to maintain the treatment interval.

Biweekly Cycle 2 and beyond (maintenance): If a dose is missed within 7 days of the scheduled date, the dose should be administered as soon as possible and the dosing schedule should be adjusted accordingly.

Missed doses exceeding 7 days: The product labeling mentions that if a dose is missed by more than 7 days during the maintenance phase (Cycle 2 and beyond), it's recommended to consult with the prescribing doctor regarding restarting treatment at a reduced dose. However, the decision to restart or adjust the dose depends on the individual patient's situation and should be made by a healthcare professional.

Have any queries, book a consultation with our Oncology Clinical Specialist

Low white blood cells count, Low Lymphocyte (type of white blood cells) count, Abdominal pain, Constipation, Diarrhea, Nausea, Vomiting, Fatigue, Swelling, Infusion-related reaction, Infected Nails, Musculoskeletal pain, Cough, Dry skin, Shortness of breath.

Have any queries, book a consultation with our Oncology Clinical Specialist

Other drug interactions with Amivantanab is still not known.

Have any queries, book a consultation with our Oncology Clinical Specialist

Amivantamab is not recommended for pregnancy. It may harm the unborn baby.

Use caution if you have liver or kidney problems. Amivantamab may affect these organs.

 Consult your doctor before taking Amivantamab if you are pregnant, breastfeeding, or have liver or kidney issues.

Have any queries, book a consultation with our Oncology Clinical Specialist